Proceedings from a daylong symposium hosted in partnership with Florida Cancer Specialists, featuring key clinical presentations and papers in gastrointestinal cancers. Featuring perspectives from Drs Johanna Bendell and Axel Grothey, including the following topics: Introduction Metastatic Colorectal Cancer Gastric Cancer Hepatocellular Carcinoma Pancreatic Adenocarcinoma Advanced Cholangiocarcinoma with an Activating FGFR2 Rearrangement CME information and select publications