Multitumor | Virtual Molecular Tumor Board:  Recognition and Management of Targetable Tumor Mutations in Less Common Cancer Types

published 1 month ago by Dr Neil Love

Proceedings from the third in a 3-part webinar series. Featuring perspectives from Drs Marcia S Brose, Andrew McKenzie and Milan Radovich, including on the following topics: Part 1: Molecular Tumor Board Introduction (00:00) Case: A woman in her late 70s with ER-positive, HER2-negative metastatic breast cancer (ESR, CHEK2 and RET mutations) — Sulfi Ibrahim, MD (6:09) Case: A woman in her mid-40s with metastatic thymoma (MTOR gain-of-function mutation) — Milan Radovich, PhD (13:29) Case: A patient with leiomyosarcoma (BRCA germline mutation) — Andrew McKenzie, PhD (15:05) Case: A patient with bone-only disease — Dr Ibrahim (16:44) Part 2: New Molecular Targets in Thyroid Cancer Case: A woman in her late 30s with RAI-refractory papillary thyroid cancer — Marcia S Brose, MD, PhD (21:25) Case: A man in his late 60s with papillary thyroid cancer — Dr Brose (29:25) Case: A woman in her late teens with locally advanced medullary thyroid cancer — Dr Brose (36:04) Case: A frail woman in her late 70s with metastatic papillary thyroid cancer (CAD) — Dr Ibrahim (39:46) Case: A man in his late 50s with metastatic thyroid cancer (RET M918T gain-of-function mutation) — Dr Radovich (43:40) Case: A man in his early 70s with metastatic medullary thyroid cancer (RET mutation) — Dr McKenzie (46:27) Part 3: Targeting the FGFR Signaling Pathway in Cholangiocarcinoma Case: A woman in her late 50s with metastatic cholangiocarcinoma (FGFR2-BICC1 fusion) — Dr Radovich (48:28) Part 4: New Options in the Management of GIST Harboring PDGFR Mutations Case: A patient with GIST (PDGFRA) — Dr McKenzie (52:57) Case: A woman in her early 60s with metastatic GIST (gain-of-function PDGFRA D842Y mutation) — Dr Radovich (54:23) Part 5: Molecular Tumor Board (Continued) Case: A man in his late 70s with metastatic pancreatic cancer (EGFR exon 19 deletion) — Justin Peter Favaro, MD, PhD (55:30) CME information and select publications

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