Getting to the Heart of Cell Fate Control

published 2 months ago by UCTV

Laurie A, Boyer, PhD, Associate Professor of Biology and Biological Engineering at MIT, discusses her work studying cell fate and cardiac regeneration. She shares how her lab is dissecting the gene regulatory mechanisms that control lineage commitment during heart development and congenital heart defects and applying this knowledge toward engineering cardiac tissues. Series: "The Stem Cell Channel" [Professional Medical Education] [Show ID: 33775]

We really started I really started thinking about stem cells as a post doc on the first stem cells embryonic stem cells from the mouse were isolated in the 19 eighties and it quickly became apparent that this was going to be a revolutionary tool for making transgenic animals but I don't think at the time it was totally appreciated how the stem cells from mouse would open the door to cell therapies. I'm in my interest really came from this I have passion I have for unraveling the mechanistic underpinning paintings of mammalian gene expression programs during development and how these programs when they go awry can cause disease ...

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